- No increase in yields; on the contrary GM soya decreased yields by up to 20 percent compared with non-GM soya , and up to 100 percent failures of Bt cotton have been recorded in India . New studies confirmed these findings. Research from the University of Kansas found a 10 percent yield drag for Roundup Ready soya  that required extra manganese applied to the soil to make up the yield deficit. A team of scientists from the USDA and the University of Georgia found growing GM cotton in the US could result in a drop in income by up to 40 percent [10, 11] (Transgenic Cotton Offers No Advantage, SiS 38)
- No reduction in pesticides use; on the contrary, USDA data showed that GM crops increase pesticide use by 50 million pounds from 1996 to 2003 in the United States .
New data paint an even grimmer picture:
- The use of glyphosate on major crops went up more than 15-fold between 1994 and 2005, along with increases in other herbicides  in order to cope with rising glyphosate resistant superweeds . Roundup tolerant canola volunteers are top among the worries of Canadian farmers [13, 14] (Study Based on Farmers' Experience Exposes Risks of GM Crops, SiS 38).
- Roundup herbicide is lethal to frogs and toxic to human placental and embryonic cells . Roundup is used in more than 80 percent of all GM crops planted in the world.
- GM crops harm wildlife, as revealed by UK's farm scale evaluations , and more recently in a study led by Loyola University, Chicago, Illinois in the United Stated, which found that wastes from Bt corn impaired the growth of a common aquatic insect [15, 16] (Bt Crops Threaten Aquatic Ecosystems, SiS 36).
- Bt resistance pests and Roundup tolerant superweeds render the two major GM crop traits practically useless . A recent review concluded that  "evolved glyphosate-resistant weeds are a major risk for the continued success of glyphosate and transgenic glyphosate-resistant crops."? And the evolution of Bt resistant bollworms worldwide have now been confirmed and documented in more than a dozen fields in Mississippi and Arkansas between 2003 and 2006 .
- Vast areas of forests, pampas and cerrados lost to GM soya in Latin America, 15 m hectares in Argentina alone ; and this has worsened considerably with the demand for biofuels (see later).
- Epidemic of suicides in the cotton belt of India involving 100 000 farmers between 1993-2003, and a further 16 000 farmers a year have died since Bt cotton was introduced .
- Transgene contamination unavoidable, scientists find GM pollination of non-GM crops and wild relatives 21 kilometres away .
- GM food and feed linked to deaths and sicknesses both in the fields in India and in lab tests around the world (more below).
- GM food and feed inherently hazardous to health .
Here are some highlights from our GM Science dossier  on the hazards of GM food and feed: - Dr. Irina Ermakova of the Russian Academy of Sciences showed how GM soya made female rats give birth to severely stunted and abnormal litters, with more than half dying in three weeks, and those remaining are sterile. - Hundreds of villagers and cotton handlers in India suffer allergy-like symptoms, thousands of sheep died after grazing on the Bt cotton residues, goat and cows as well were reported in 2007 and 2008  (Mass Protests against GM Crops in India, SiS 38). - A harmless bean protein transferred to pea when tested on mice cause severe inflammation in the lungs and provoked generalised food sensitivities. - Dozens of villagers in the south of the Philippines fell ill when neighbouring GM maize fields came into flower in 2003, five have died and some remain ill to this day. - A dozen cows died having eaten GM maize in Hesse Germany and more in the herd had to be slaughtered from mysterious illnesses. - Arpad Pusztai and his colleagues in the UK found GM potatoes with snowdrop lectin damaged every organ system of young rats; the stomach lining grew twice as thick as controls. - Chickens fed GM maize Chardon LL were twice as likely to die as controls. - And finally, GM maize Mon 863 was claimed to be as safe as non-GM maize by the company, and accepted as such by European Food Safety Authority. But independent scientists of CriiGen in France re-analysed the data and found signs of liver and kidney toxicity.  Ho MW. Genetic Engineering Dream of Nightmare? The Brave New World of Bad Science and Big Business, Third World Network, Gateway Books, MacMillan, Continuum, Penang, Malaysia, Bath, UK, Dublin, Ireland, New York, USA, 1998, 1999, 2007 (reprint with extended Introduction).  Ho MW. Living with the Fluid Genome, ISIS & TWN, London and Penang, 2003.  Ho MW. Life beyond the Central Dogma series, Science in Society 24, 4-13, 2004.  Ho MW and Lim LC. The Case for a GM-Free Sustainable World, Independent Science Panel Report, Institute of Science in Society and Third World Network, London and Penang, 2003; republished GM-Free, Exposing the Hazards of Biotechnology to Ensure the Integrity of Our Food Supply, Vitalhealth Publishing, Ridgefield, Ct., 2004 (both available from ISIS online bookstore.  Lim LC. Keep GM out of Europe! Science in Society 24, 26-27, 2004.  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